Will ISA slots hold up in my projects?

Will ISA slots hold up in my projects? isa slot ISA Slots Motherboard isa slot adapter Adek Industrial makes ATX mobos with ISA slots Looks like they only offer one model per CPUmemory generation Here's the MB-P4BWA Industrial

isa slot adapter 4 Slot ISA-PCIE Backplane Specifications 4 ISA slots 1 PCIE slot, 1 shares with ISA slot 1 ATX Power connector One 4-pin JST Connector 2 LEDs

isa slot The ISA slot connector is typically black, distinguishing it from the brown EISA connectors and white PCI connectors The ISA bus, which initially included ISA Slot Motherboard · Supports Intel Core 2 Quad, Core 2 Duo Pentium D LGA775 processors 5338001066 FSB · 4 x 240-pin DDR2 533667800 MHz RAM up to 8 GB